Scientists have documented the benefits of lactate burning in exercising humans, but few studies have looked at the role of lactate during rest or after a meal. Exercise physiologists challenged fasting men and women with a carbohydrate meal and then monitored lactate in the blood and fat vs carbohydrate metabolism. They found that lactate buffers glucose from a meal, and that lactate is utilized for energy almost as much as glucose.
Read more …Far from toxic, lactate rivals glucose as body's major fuel after a carbohydrate meal

Environmentally caused alterations to specific areas of the genome -- known as imprint control regions -- during early development may contribute to the risk of developing Alzheimer's disease, and Black people may be more affected than white people.
Read more …Study explores role of epigenetics, environment in differing Alzheimer's risk between Black and...

Engineers have discovered that some brain cells age more rapidly than others, and they are disproportionately abundant in individuals afflicted with Alzheimer's disease. Additionally, researchers observed male-female-specific differences in the aging process of certain brain cells, with the female cortex exhibiting a higher ratio of 'old' oligodendrocytes to 'old' neurons compared to the male cortex. The discoveries were made possible by a new technique called MUSIC (multinucleic acid interaction mapping in single cells), which allows researchers to peek inside individual brain cells and map out interactions between chromatin--which is the tightly coiled form of DNA -- and RNA.
Read more …Some brain cells age faster and are more prevalent in Alzheimer's

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