Researchers have discovered that some CAR-T cells engineered to fight cancer and other conditions carry the memory of past encounters with bacteria, viruses and other antigens within them, a finding that may allow scientists to manufacture the cells in more precise and targeted ways.
Read more …CAR-T cells hold memories of past encounters
A new study uncovers how a novel immunotherapy prevents squamous cell carcinoma, with benefits lasting five years after treatment. This therapy is the first to activate specific components of the adaptive immune system, particularly CD4+ T helper cells, which are not known to be involved in traditional cancer treatments. This work highlights the potential for similar immunotherapies to prevent other cancers throughout the body.
Read more …Cancer-preventing topical immunotherapy trains the immune system to fight pre-cancers
An ancient brain circuit, which enables the eyes to reflexively rotate up as the body tilts down, tunes itself early in life as an animal develops, a new study finds.
Read more …Newborn brain circuit stabilizes gaze