People who climb too fast or too high risk acute altitude sickness, which can lead to life-threatening hypoxic brain injury. By using in vivo electrochemistry, researchers demonstrated that characteristic changes occur in the oxygen content of various brain regions before injury. The risk of brain damage could be predicted days in advance -- perhaps a new approach for detecting high-altitude hypoxic injury.
Read more …Early detection of high-altitude hypoxic brain injury

Scientists report on new insights into the mechanisms of 'Niemann-Pick type C' (NPC), a rare neurodegenerative disease associated with dementia that can manifest as early as childhood. Their findings, based on studies in mice, cell cultures and patients, emphasize that neuroinflammation, which is mediated by the brain's immune system, plays a crucial role in NPC.
Read more …New insights into NPC: A form of childhood dementia

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