Although sedentary behavior may be an evolutionarily selected trait, it is still important to try to be physically active, says a new study. Researchers have shown for the first time that genetic predisposition to sedentary behavior is associated with a higher risk of developing the most common cardiovascular diseases. A high genetic predisposition to sedentary behavior can increase the risk of cardiovascular diseases by up to 20%.
Read more …Genetic predisposition to sedentary behavior increases the risk of cardiovascular diseases
Organoids are made to model human organs and are promising for research and therapy, but there are limitations in their growth and function. A recent study found that placenta-derived IL1 under hypoxic conditions, can greatly increase growth of human stem cell-derived liver organoids. By promoting liver progenitor cell expansion through a specific signaling pathway, this method offers a promising route to improve organoid models and regenerative medicine.
Read more …Mimicking embryonic growth to break barriers in organoid research