A research team has identified a crucial mechanism on a specific cell receptor that can cause cells to self-destruct. Being able to activate the receptor -- Fas -- and trigger cell death could open the door for improved cancer treatments. Modulating Fas may also extend the benefits of chimeric antigen receptor (CAR) T-cell therapy to solid tumors.
Read more …Researchers identify 'switch' to activate cancer cell death
A new study sheds light on the vital role of communication and expertise within organizations, revealing their impact on group performance. Researchers examined how individuals become part of communication networks and the effect of selection processes on group performance. The study found that people who communicated more during training were more likely to be chosen as a central member of the network. In addition, teams that chose their central member performed as well as and often better than teams whose central member was randomly assigned.
Read more …People who communicate more, show expertise are more likely to be seen as essential team members
An international team of researchers has provided valuable insights into the brain's noradrenaline (NA) system, which has been a longtime target for medications to treat attention-deficit/hyperactivity disorder, depression, and anxiety. Equally important beyond the findings is the groundbreaking methodology that the researchers developed to record real-time chemical activity from standard clinical electrodes which are routinely implanted for epilepsy monitoring.
Read more …Researchers use pioneering new method to unlock brain's noradrenaline system